Niemann-Pick disease

Niemann-Pick disease is any of a group of lysosomal storage diseases, transmitted genetically, with the common effect of sphingomyelin storage in various tissues of the body. The tissues affected the worst by the disorder are the brain, spleen, and the lungs.

The disorder is characterized by a deficiency of sphingomyelinase, which results in an accumulation of sphingomyelin and cholesterol in various cells.

This article is licensed under the GNU Free Documentation License. It uses material from Wikipedia article. Browse Wikipedia for more information.