Figure 1 Drosophila melanogaster oogenesis

Females first mate about 8 hours after emergence. The females store sperm from previous males they mated with for later use. For this reason geneticists must collect the female fly before her first mating, that is, a virgin female, and ensure that she mates only with the particular male needed for the experiment.

Drosophila melanogaster was chosen as a genetic animal model at the beginning of the twentieth century by Nobel Prize winner Thomas Hunt Morgan. Since then it has been a very successful animal model for biological research, for several reasons:

• It is small and easy to grow in the laboratory.
• It has only 4 chromosomes.
• Males do not show recombination, facilitating genetic studies.
• Genetic transformation techniques have been available since 1987.
• Its compact genome was sequenced in 1998.

In the molecular biology community, Drosophila geneticists are known for their relatively whimsical naming of discovered gene mutations. Compared to the stodgy (but perhaps more practical) "cdc4", "cdk4", etc. names in the yeast genome, Drosophila sports such favorites as "cheap date" (a mutation leading to increased sensitivity to ethanol intoxication) and "snafu" (a mutation leading to grotesque anatomical abnormalities).

See also

• Drosophila embryogenesis

External links

• The WWW Virtual Library: Drosophila (http://www.ceolas.org/VL/fly/)
• The Berkeley Drosophila Genome Project (http://www.fruitfly.org/)
• Keeping and Breeding Fruit Flies (http://www.easyinsects.co.uk/livefood/fruitflies/)
• Abstract of the papers describing the genome of Drosophila melanogaster (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10731132&dopt=Abstract)

da:Bananflue (Drosophila melanogaster) de:Drosophila melanogaster es:Drosophila melanogaster ko:초파리